Bacterial ribosomes are central to protein synthesis, and their regulation is vital for adaptation to environmental stresses. Under conditions such as nutrient deprivation, cold shock or hypoxia, ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

He ripped the ribosome open, literally. And, it became an important step in the production of antibiotics. In 2000, using a method known as x-ray crystallography, Venkatraman Ramakrishnan and other ...

Led by Northwestern Engineering’s Michael Jewett, researchers created a new version of an engineered tethered ribosome dubbed Ribo-T, which provides a foundation to propel broad, new efforts in ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Researchers have identified a four-protein complex that appears to play a key role in generating ribosomes -- organelles that serve as protein factories for cells -- as well as a surprising part in ...

A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick. Co-authored by researchers from the ...

Angiogenin is a well-characterized enzyme that has a variety of important roles; it can trigger the growth of new blood vessels, is involved in cell survival, migration, and proliferation, and has ...

Existing bacteria and archaea still our universal common ancestor’s ribosomal hibernation defense mechanism when nutrients are scarce.