A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

相同組換えによってDNAが修復される際には、最終段階でDNA合成が起こる。今回、DNAヘリカーゼPif1がこの反応で果たす役割が、2つの論文によって明らかになった。Pif1がない場合、DNA鎖切断により誘発される複製（break-induced replication；BIR）の初期段階は正常に ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...