Researchers have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha ...

Osaka, Japan – Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production. Now, in a study ...

Pharmaceuticals generally contain a few tens of atoms and a similar number of chemical bonds between the atoms. Thus, designing complex drug architectures from simple precursors using the techniques ...

When chemists design drug candidates, shape matters enormously. Many active pharmaceutical ingredients contain branched carbon ...

Using fundamental calculations of molecular interactions, they created a catalyst with 100% selectivity in producing propylene, a key precursor to plastics and fabric manufacturing Researchers at ...

When chemists design drug candidates, shape matters enormously. Many active pharmaceutical ingredients contain branched ...

A chemical reaction that's vital to a range of commercial and industrial goods may soon be initiated more effectively and less expensively. A chemical reaction that's vital to a range of commercial ...